Different featured image position/location within post for category X

Hello,

If I would like the posts from a category in my blog to have a different setting from those set in Customizer what is the best way to do this?

eg. if Customizer is:
Location: Above Title
Alignment: left
Size 123 x100

And I want all the posts in category 123 to be:
Location: Below 1st paragraph
Alignment: center
Size: large

What is the best way to do this?

Thanks